Endocrine Abstracts

The kisspeptin, the peptide product of KiSS-1 gene has recently emerged as essential gatekeeper of pubertal activation of gonadotropin-releasing hormone neurons and the reproductive axis. Mutations or targeted disruptions in the gene cause hypogonadism or premature sexual development and sterility.Purpose: The study was undertaken to research the kisspeptin levels in healthy girls and girls with endocrine and gynaecological disorders.<p class=...

Introduction: The breast is a hormone-dependent organ.Purpose: To study hormonal disorders peculiarities and breast diseases in adolescent girls.Patients and methods: Examined were 867 adolescent girls (aged 12–18), including 154 girls with breast diseases and dysmorphogenies (macromastia, hypoplasia, striae). The questioning, total clinical examination, hormonal analysis and ultrasound examination were conducted. Data are exp...